Neuro Immune Connections, MMR Vaccine, Autism and a CDC Whistleblower
Scientists have revealed many neuro-immune connections, a link between the immune system and the brain. This phenomenon is influencing social behavior. The CDC has manipulated studies which are clearly indicating that an MMR vaccine can cause Autism.
CDC Whistleblower Dr William Thomson confesses to MMR vaccine research fraud in historic public statement.
Quote: "It’s a stunning discovery that overturns decades of textbook teaching: researchers at the School of Medicine have determined that the brain is directly connected to the immune system by vessels previously thought not to exist. “I really did not believe there were structures in the body that we were not aware of. I thought the body was mapped,” said Jonathan Kipnis, a professor in the Department of Neuroscience and director of the University’s Center for Brain Immunology and Glia. How these vessels could have escaped detection when the lymphatic system has been so thoroughly mapped throughout the body is surprising on its own.
But the true significance of the discovery lies in its ramifications for the study and treatment of neurological diseases ranging from autism to Alzheimer’s disease to multiple sclerosis. Kipnis said researchers no longer need to ask questions such as, “How do we study the immune response of the brain?” or “Why do multiple sclerosis patients have immune system attacks?” “Now we can approach this mechanistically — because the brain is like every other tissue connected to the peripheral immune system through meningeal lymphatic vessels,” Kipnis said. “We believe that for every neurological disease that has an immune component to it, these vessels may play a major role.” Kevin Lee, who chairs the Department of Neuroscience, recalled his reaction the first time researchers in Kipnis’ lab shared their basic result with him."
"I just said one sentence: ‘They’ll have to rewrite the textbooks.’ There has never been a lymphatic system for the central nervous system, and it was very clear from that first singular observation — and they’ve done many studies since then to bolster the finding — that it will fundamentally change the way people look at the central nervous system’s relationship with the immune system,” Lee said." Unquote
Quote by University of Virginia (UVA Today): "In a startling discovery that raises fundamental questions about human behavior, researchers at the University of Virginia School of Medicine have determined that the immune system directly affects – and even controls – creatures’ social behavior, such as their desire to interact with others.
So could immune system problems contribute to an inability to have normal social interactions? The answer appears to be yes, and that finding could have significant implications for neurological diseases such as autism-spectrum disorders and schizophrenia.
“The brain and the adaptive immune system were thought to be isolated from each other, and any immune activity in the brain was perceived as sign of a pathology. And now, not only are we showing that they are closely interacting, but some of our behavior traits might have evolved because of our immune response to pathogens,” explained Jonathan Kipnis, chair of UVA’s Department of Neuroscience. “It’s crazy, but maybe we are just multicellular battlefields for two ancient forces: pathogens and the immune system. Part of our personality may actually be dictated by the immune system.”
Quote by Neuroscience News: "The researchers note that a malfunctioning immune system may be responsible for “social deficits in numerous neurological and psychiatric disorders.” But exactly what this might mean for autism and other specific conditions requires further investigation.
NeuroscienceNews.com image is adapted from the University of Virginia School of Medicine press release."
Autism can be caused by an immune response and being grasped by a systemic approach called systems biology. Autism is not caused by a mental disorder but by neuro-immune connections, an area called neuroimmunology. This is closely related to the lymphatic drainage system: Quote (Nature): " Although it is now accepted that the central nervous system undergoes constant immune surveillance that takes place within the meningeal compartment the mechanisms governing the entrance and exit of immune cells from the central nervous system remain poorly understood. In searching for T-cell gateways into and out of the meninges, we discovered functional lymphatic vessels lining the dural sinuses. These structures express all of the molecular hallmarks of lymphatic endothelial cells, are able to carry both fluid and immune cells from the cerebrospinal fluid, and are connected to the deep cervical lymph nodes. The unique location of these vessels may have impeded their discovery to date, thereby contributing to the long-held concept of the absence of lymphatic vasculature in the central nervous system. The discovery of the central nervous system lymphatic system may call for a reassessment of basic assumptions in neuroimmunology and sheds new light on the aetiology of neuroinflammatory and neurodegenerative diseases associated with immune system dysfunction." Unquote
This is something that Henry Markram will never figure out by his mathematical models!
Unexpected role of interferon-γ in regulating neuronal connectivity and social behaviour (Nature),
"Immune dysfunction is commonly associated with several neurological and mental disorders. Although the mechanisms by which peripheral immunity may influence neuronal function are largely unknown, recent findings implicate meningeal immunity influencing behaviour, such as spatial learning and memory1. Here we show that meningeal immunity is also critical for social behaviour; mice deficient in adaptive immunity exhibit social deficits and hyper-connectivity of fronto-cortical brain regions. Associations between rodent transcriptomes from brain and cellular transcriptomes in response to T-cell-derived cytokines suggest a strong interaction between social behaviour and interferon-γ (IFN-γ)-driven responses. Concordantly, we demonstrate that inhibitory neurons respond to IFN-γ and increase GABAergic (γ-aminobutyric-acid) currents in projection neurons, suggesting that IFN-γ is a molecular link between meningeal immunity and neural circuits recruited for social behaviour. Meta-analysis of the transcriptomes of a range of organisms reveals that rodents, fish, and flies elevate IFN-γ/JAK-STAT-dependent gene signatures in a social context, suggesting that the IFN-γ signalling pathway could mediate a co-evolutionary link between social/aggregation behaviour and an efficient anti-pathogen response. This study implicates adaptive immune dysfunction, in particular IFN-γ, in disorders characterized by social dysfunction and suggests a co-evolutionary link between social behaviour and an anti-pathogen immune response driven by IFN-γ signalling." Unquote
VAXXED, Dr Andrew Wakefield, the Lancet and more fraud by CDC Scientists
In 1998, Dr Andrew Wakefield has published a research paper about "Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children" in the Lancet Magazine. This research by Andrew Wakefield has been unjustifiably discredited by many of his colleagues and he was forced to retract the study, accused of fraud and discredited as a scientist.
Despite to all those allegations, Andrew Wakefield, MB.BS, an academic gastroenterologist, moved to Texas in order to prove his claims, a task that he successfully managed. Andrew Wakefield was fully rehabilitated.
Quote by John Hewitt on Twitter: There's 2 Eisens in the progressive academic sphere and they are both total wackjobs. both want our minds controlled by microbiome. M. Eisen, PlosOne editor, has publicly called anyone watching 'Vaxxed' an accessory to murder, that tells you something of his fear.
Link between antibiotics in early childhood and autism
Quote: "Host microbiota control maturing and functioning of brain immune cells / Short-chain fatty acids function as messengers between the gut and the brain / Publication in Nature Neuroscience
The gut's microbiome has an impact on the brain's immune response throughout life, with a possible effect on the course of diseases affecting the brain, such as Alzheimer's disease or multiple sclerosis. A neuropathological research team at the University Medical Center Freiburg has uncovered these effects in mice. The scientists have been able to demonstrate that the function of microglia, also called brain macrophages, is controlled by metabolites of gut bacteria. During the digestion of fibres, in particular, intestinal bacteria produce short-chain fatty acids necessary for proper microglia function. Mice whose intestines were free of bacteria developed immature and stunted microglia. When intestinal flora was reintroduced, microglia cell morphology and function recovered. This study highlights the importance of a balanced diet for the prevention of brain diseases and indicates that there may be a link between gut bacteria and the genesis of neurodegenerative diseases. These findings will be published in the July issue of the renowned journal Nature Neuroscience and already available as advance online publication.
Microglia are also known as phagocytes of the brain, or brain macrophages. They eliminate invading pathogens and dead brain cells, thus contributing to the brain's life-long plasticity. Malfunctioning microglia cells play a role in a number of brain diseases. Until now, the maturing and activation of these cells has been unclear."
Some Explanations, Quantum Biology, Demise of the Central Dogma of Molecular Biology and Surface Physics
This works by a similar mechanism that works via antibiotics as well, especially when the combined vaccine for measles, mumps and rubella or MMR-Vaccine is applied in early childhood (the stress is on "early") by an immune response via enteric flora (ENS, Enteric Nervous System) and neurons in conjunction with microorganisms, the lymphatic system, short chain fatty acids and scavenger cells which are influencing the Brain/CNS/Microglia, overcoming the blood cerebral barrier.
The link between an MMR Vaccine and autism is obvious but it is NOT about an anti-vaxxer movement, stop to think in terms of pro vaccination and anti-vaccination. Statistics and studies are misleading about what happens on a global scale.
It is no about an imperative mechanism which is enforcing something, for instance a 'disease', which is a human classification, neglecting the high variability of pathogens. Every human being is a random sample, microorganisms are 'reproducing' themselves in a random process (look up Bet Hedging), it is not a 'process' at all (classic world view) but happens on quantum level.
P-values should not be abused, they are derived by a post Gauß'ian observation (visible light), they are debunked by quantum biology, which says that there is no attribution of cause and effect in the observable world, means that dna cannot be described properly by a static model. There is no direct link between a 'disease' and genetics.
These questions are legit: is there any disease in nature? What does it mean when scientists claim to have exterminated a "disease"?
Is there a mismatch between these claims and our observations or our interpretations of our observations?
More appropriate and effective ways in order to protect human beings from a disease are to strengthen their adaptability and their immune system, preparing them for an ongoing change (pathogens) and to research possible causes for health related problems, applying models taking into account multi-causality. Assertions derived by a 'vaccination coverage rate' (by 95% of the targeted population in case of the MMR Vaccine, proposed by the German Robert Koch Institute, RKI) is neglecting this.
In the case of for instance Yersinia pestis, a weakening of the immune system by a small climate shift (no more rain) causing crop failure has prepared the "success" of this virus within the population of the 14th century in Europe (yersinia pestis exists since the Bronze Age or even longer). Small pox was not exterminated as well, the same for poliomyelitis: new outbreaks have been reported recently (2016). The polio vaccine is contaminated with SV40, a cancer virus.
Every human being is a random sample, the same for microorganisms, DNA is not determining who we are:
1. p-values are debunked
2. Look up 'Dark Matter of our genome' The demise of the Central Dogma of Molecular Biology.
3. Spatial alignment and quantum properties reveal the mistakes made by Crick and Watson:
The interpretation of DNA as a static model with base pairs and a double-helix structure is not taking into account the 'Dark Matter' of our genome. Crick and Watson were even not able to figure out an appropriate interpretation of the double helix structure (guess who has done this?), DNA is just a basic pattern which permanently transforms and is being transformed by, for instance, epigenetics, proteomics, junk-dna, RNA viruses, virome, trans-splicing, transposons, prions, gene rearrangements and so forth, but the more appropriate model is a quantum state model that is not interfering in a 3D world but within topological layers and a permanent phase transition, indicated by quantum markers, in view to permanent changes, by, for instance, surface physics (for instance docking mechanism for T-Cells or Antibodies), epigenetics or protein membrane foldings. These are metastatical states on quantum level.
Further reading and sources:
John Hewitt on Twitter: "discovery was very well hyped, definitely many neuro-immune connections"